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Integration of pharmacokinetics, pharmacodynamics, and toxicokinetics in rational drug development Papers pres. at a conf. entitled "The Integration of pharmacokinetic, pharmacodynamic, a. toxicokinetic principles in rational drug development", held Apr. 24-26, 1991, in Arlington, Virginia Spons. by the Amer. assoc. of pharmaceutical scientists etc. ; Ed. by Avraham Yacobi et al.